Home Current Archive Editorial board
News Contact
Original Scientific Articles

Examining 25-Year Trends of Type 1 Diabetes Incidence in Pediatric Population Aged 0-14 of the Republic of Srpska

Gordana Bukara-Radujković
Gordana Bukara-Radujković
Contact Gordana Bukara-Radujković

Paediatric Clinic, University Clinical center of the Republic of Srpska, Banja Luka, Bosnia and Herzegovina

Department of Paediatrics, Faculty of Medicine , University of Banja Luka, Banja Luka, Bosnia and Herzegovina

Editor: Siniša Ristić


Introduction. Data on newly diagnosed cases of type 1 diabetes and the incidence of this disease are very significant. Studies like this one, with an analysis of incidence over the past 25 years, help not only locally but also globally.
Methods. The primary source of data is hospital records from hospital centers in Republic of Srpska. The secondary, confirmatory source, is the data from the Health Insurance Fund of Republic of Srpska through which all newly diagnosed patients receive insulin and blood glucose testing strips. 
Results. The average incidence for the entire period was 12.8/100,000 (95% CI: 10.40–15.22), with a total of 527 cases, of which 265 (50.3%) were boys. Positive linear trend was observed (R=0.747, R2=0.558, p=0.000018). The annual increase was 0.59 (95% CI: 0.37– 0.82) or 29.06%. There was no difference between sexes, and the highest incidence, number, and growth were in the age group of 10–14 years.
Discussion. Compared to the period 2001–2016 (11/100,000) and to the period 1998–2010 (7.5/100,000), there was the increase in incidence. Significant increase in incidence was observed in the period 2017–2022. There is no difference from the rest of the world regarding incidence by sex, but there is regarding age group, with the highest incidence in the 10–14 age group. 
Conclusion. This research provides a good basis for future studies on the impact of environmental, medical, and other factors on the onset of type 1 diabetes, as well as potential local, national, and global diabetes prevention programs.

Author Contributions

Conceptualization, G.B.; Data curation, G.B.; Formal Analysis, G.B.; Funding acquisition, G.B.; Investigation, G.B.; Methodology, G.B.; Project administration, G.B.; Resources, G.B.; Software, G.B.; Supervision, G.B.; Validation, G.B.; Visualization, G.B.; Writing – original draft, G.B.; Writing – review & editing, G.B. All authors have read and agreed to the published version of the manuscript.


Data Availability

Data presented in this paper can be presented upon request

Funding Statement

The author received no external funding.

Authors retain copyright. This work is licensed under a Creative Commons Attribution 4.0 International License. Creative Commons License

Article metrics

Google scholar: See link

The statements, opinions and data contained in the journal are solely those of the individual authors and contributors and not of the publisher and the editor(s). We stay neutral with regard to jurisdictional claims in published maps and institutional affiliations.