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30.06.2022.

Original Scientific Articles

Magnetic resonance imaging of the heart as a method of long-term monitoring of right heart function after tetralogy of Fallot surgery

By Biljana Milinković, Jelena Milić, Dejan Bokonjić, Verica Prodanović, Bojan Joksimović, Siniša Ristić

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Edited by:

Prof. Siniša Ristić MD, PhD

Vol 14, No 2 (2023):

Biomedicinska istraživanja

Published: 29.12.2023.

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19.06.2024. Original Scientific Articles Online First
Examining 25-Year Trends of Type 1 Diabetes Incidence in Pediatric Population Aged 0-14 of the Republic of Srpska

By Gordana Bukara-Radujković

Introduction. Data on newly diagnosed cases of type 1 diabetes and the incidence of this disease are very significant. Studies like this one, with an analysis of incidence over the past 25 years, help not only locally but also globally.
Methods. The primary source of data is hospital records from hospital centers in Republic of Srpska. The secondary, confirmatory source, is the data from the Health Insurance Fund of Republic of Srpska through which all newly diagnosed patients receive insulin and blood glucose testing strips. 
Results. The average incidence for the entire period was 12,800/100,000 (95% CI: 10.40–15.22), with a total of 527 cases, of which 265 (50.3%) were boys. Positive linear trend was observed (R=0.747, R2=0.558, p=0.000018). The annual increase was 0.59 (95% CI: 0.37– 0.82) or 29.06%. There was no difference between sexes, and the highest incidence, number, and growth were in the age group of 10–14 years.
Discussion. Compared to the period 2001–2016 (11/100,000) and to the period 1998–2010 (7.5/100,000), there was the increase in incidence. Significant increase in incidence was observed in the period 2017–2022. There is no difference from the rest of the world regarding incidence by sex, but there is regarding age group, with the highest incidence in the 10–14 age group. 
Conclusion. This research provides a good basis for future studies on the impact of environmental, medical, and other factors on the onset of type 1 diabetes, as well as potential local, national, and global diabetes prevention programs. 

19.06.2024. Reviews Online First
Contribution of tractography to neuroanatomical terminology - short association tracts of the frontal lobe

By Slobodan Malobabić, Goran Spasojević

Enormous development of neuroimaging technologies, and subsequently of research methods, opened new era of in vivo research of the white matter anatomy. This review analyzes recent connectomics and imaging data about short association fibers of the frontal lobe, and relates it to current status and to further development of anatomical terminology. In some recent terminologies, such as in Neuroanatomical Terminology, or in Terminology of German Anatomical Society, under the section Fibrae associationis lobares Fasciculus frontalis obliquus, Fasciculus frontalis orbitopolaris and Fasciculus frontomarginalis have been listed. Also, in this review anatomy of the potential candidates for adding into new terminologies is described, such as Fronto-parietal U-tracts, Fronto-insular tracts, and Frontal longitudinal fasciculus system. Suggestions considered in this review are related to our research of human brain morphology in order to overcome the lack of postmortem brain specimens, to contribute to the linking of different data, and to enable better morphological correlations.  

19.06.2024. Original Scientific Articles Online First
Attitude of healthcare workers towards information technology

By Dajana Milidrag, Aleksandar Tanović, Igor Medenica, Lado Davidović

Introduction. Data on newly diagnosed cases of type 1 diabetes and the incidence of this disease are very significant. Studies like this one, with an analysis of incidence over the past 25 years, help not only locally but also globally.
Methods. The primary source of data is hospital records from hospital centers in Republic of Srpska. The secondary, confirmatory source, is the data from the Health Insurance Fund of Republic of Srpska through which all newly diagnosed patients receive insulin and blood glucose testing strips. 
Results. The average incidence for the entire period was 12,800/100,000 (95% CI: 10.40–15.22), with a total of 527 cases, of which 265 (50.3%) were boys. Positive linear trend was observed (R=0.747, R2=0.558, p=0.000018). The annual increase was 0.59 (95% CI: 0.37– 0.82) or 29.06%. There was no difference between sexes, and the highest incidence, number, and growth were in the age group of 10–14 years.
Discussion. Compared to the period 2001–2016 (11/100,000) and to the period 1998–2010 (7.5/100,000), there was the increase in incidence. Significant increase in incidence was observed in the period 2017–2022. There is no difference from the rest of the world regarding incidence by sex, but there is regarding age group, with the highest incidence in the 10–14 age group. 
Conclusion. This research provides a good basis for future studies on the impact of environmental, medical, and other factors on the onset of type 1 diabetes, as well as potential local, national, and global diabetes prevention programs. 

19.06.2024. Reviews Online First
Dry needling in cervical pain therapy: literature review

By Bojan Pavlović, Ana Pavlović

19.06.2024. Reviews Online First
Patients’ satisfaction with the quality healthcare services

By Tamara Milosavljević, Nina Stoičević, Dragan Ivanović

31.05.2024. Reviews Online First
Treatment approaches of central auditory processing deficit

By Sladjana Calasan, Sofija Bajagić, Branislava Ćurčić

16.04.2024. Original Scientific Articles Online First
Two-tiered serology in patients with Lyme neuroborreliosis

By Tatjana Roganović, Miloš Korać, Borut Bosančić, Višnja Mrdjen, Ljiljana Božić, Andjela Bojanić

15.04.2024. Original Scientific Articles Online First
Preeclampsia and Preterm Delivery Risk: The Significance of Obesity in Pregnancy

By Tamara Perić, Mirjana Bogavac, Zoran Belopavlović

28.12.2019. Original Scientific Articles
Impact of elapsed time between first symptoms and diagnosis of celiac disease on psycho-physical functioning and social life of children and adolescents

By Biljana Stojanović-Jovanović, Stevan Jovanović, Biljana Vuletić

Introduction. Celiac disease is an autoimmune disease resulting from an inadequate immune response to gluten in genetically predisposed individuals as a result of consuming gluten and other related proteins present in wheat, rye, barley and oats. The only cure for this specific disease is a strict, carefully controlled and lifelong gluten-free diet. The aim of the study was to evaluate whether the elapsed time between the onset of the first symptoms and the diagnosis of celiac disease affected the psycho-physical functioning and social life of children and adolescents.

Methods. The study involved 116 respondents (39 of them were males), aged 8-18 years, who were diagnosed with celiac disease. The Documentation Sheet and the Celiac-Specific Pediatric Health-Related Instrument (CDPQOL), measuring the psycho-physical functioning and social life, were used in the study.

Results. 50% of subjects, aged ≤ 2 years, were diagnosed with celiac disease. 48.28% of them were diagnosed with the disease within three months after the symptom onset. In respondents with celiac disease, aged 8-12 years, there was no statistically significant difference between the psycho-physical functioning and social life and the elapsed time between the first symptoms and the established diagnosis. In subjects aged 13-18 years, using CDPQOL, a statistically significant difference was found in the following domains: school functioning, going out and social events, self-confidence. Furthermore, there was a statistically significant difference between total CDPQOL score and the elapsed time between the first symptoms and the established diagnosis.

Conclusion. The elapsed time between the first symptoms and the established diagnosis significantly affects the psycho-physical functioning and social life of subjects aged 13-18 years, but it does not affect the psycho-physical functioning and social life of the younger respondents. This is to confirm the importance of early diagnosis and treatment initiation.

Current issue
07.11.2023. Original Scientific Articles
Knowledge and attitudes of employees at the Faculty of Medicine Foča about the concept and ethical issues in genetics

By Nikolina Elez-Burnjaković, Milena Dubravac Tanasković, Milan Kulić, Radmila Balaban Đurević, Aleksandar Tanović, Kristina Drašković Mališ, Biljana Vasiljević, Bojan Joksimović

14.11.2023. Original Scientific Articles
Methodological pluralism or multimethod research in health and medical sciences

By Srdjan Živanović, Jelena Pavlović, Natalija Hadživuković, Sandra Matović, Olivera Kalajdžić, Bojana Vuković, Ljubiša Kucurski

20.11.2023. Original Scientific Articles
Risk factors for the emergence of frailty in elderly persons in Bosnia and Herzegovina

By Natalija Hadživuković, Jelena Pavlović, Srdjan Živanović, Sandra Matović, Srdjan Mašić, Dragan Spaić, Olivera Kalajdžić, Ljubiša Kucurski, Mile Despotović

12.01.2023. Original Scientific Articles
Sports activities and psychophysical health of deaf and hard of hearing people

By Jasmina Karić B., Milena Kordić B., Vladimir Živanović R., Jana Mitrić, Siniša Šolaja, Ilija Stijepić

18.12.2023. Original Scientific Articles
Sex-dependent differences in patients treated with regular hemodialysis

By Ljubica Mitev Prokopović, Miodrag Sokolović, Branimir Haviža Lilić, Miomir Prokopović

Recent issues
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01.12.2011. Original Scientific Articles
Dijagnostika fokalnih promjena u jetri

By Zoran Terzić, Branko Brmbolić, Miloš Korać, Boban Đorđević, Dragica Terzić, Bogdanka Andrić, Siniša Ristić

Uvod. Patološki procesi u jetri mogu biti difuznog karaktera (zapaljenski,metaboličke bolesti, hematološke bolesti, toksične bolesti) i fokalne (zapaljenske,parazitarne i tumorske). Cilj rada je prikaz fokalnih promjena u jetrinomparenhimu nakon ultrazvučne, laparaskopske i patohistološke dijagnostike.Metode. Retrospektivno-prospektivnim ispitivanjem je obuhvaćeno 147punoljetnih pacijenata oba pola. Fokalne promjene jetrinog tkiva su sagledaneultrazvučnom, laparoskopskom i patohistološkom dijagnostikom.Rezultati. Osnovne karakteristike ispitanika: muškaraca 71 i žena 76 sanajvećim brojem pacijenata (102 - 70%) životne dobi između 40 i 70 godina,sa ravnomjernom distribucijom za svakih deset godina starosti. Međutim,neobično je veliki broj pacijenata ženskog pola registrovan u četvrtoj decenijiživota, čak 14 (9,5%) od ukupnog broja ispitanika, odnosno 18% odispitanika ženskog pola. Metastaze čine 104 (71%) svih fokalnih lezija jetre.U većini slučajeva radilo se o metastazama karcinoma dojke. Iako najčešćeimaju tipičnu ultrazvučnu prezentaciju, metastaze u jetri mogu da daju širokspektar različitih ultrazvučnih slikaZaključak. Najčešće fokalne promjene u jetri su metastaze adenokarcinoma.Samo 3 (2%) fokalne promjene dijagnostikovane ultrazvukom nisu potvrđenekao fokalne laparoskopskom tehnikom i patohistološkom analizom tkiva jetre.

30.06.2022. Original Scientific Articles
Voice condition assessment and the effect of rehabilitation in vocal professionals

By Mila Bunijevac, Zlatko Maksimović, Andrijana Mikić

28.06.2021. Reviews
Vitamin D and atherosclerosis

By Olivera Rašević, Maida Mulić, Maja Vuković, Vesna Lazić, Biljana Mijović, Miloš Maksimović

28.06.2021. Original Scientific Articles
The knowledge of nurses about prevention of infections caused by the bacteria Clostridium difficile

By Ivana Miljković, Amajla Topuz

01.12.2012. Original Scientific Articles
Sensibility of tactile discrimination between the fingers of the dominant and non-dominant hands

By Olivera P Spasojević, Zoran Obradović, Slavko Grbić, Marinko Domuzin, Aleksandra Grbić

Introduction. Uninjured fingers of the opposite hand are often used to control the recovery of sensibility in injured fingertips. The aim of this study is to examine the sensitivity of the surface on the fingertips between the dominant and non-dominant hand using static and dynamic two-point discrimination test and determine if there are significant differences in sensibility between the fingers of the dominant and
non-dominant hands.

Methods
. The research was done on 50 persons (500 fingers) using two-point test for measuring tactile discrimination of fingers (two-point discrimination test - 2PD). 2PD test is the most widely used test for the control of sensory recovery after nerve injury. Dynamic and static two-point discrimination method was used.
Results
. Using the static two-point discrimination test, we found out that the highest sensibility was in the index finger in both the dominant and non-dominant hand (dominant, 2.78 ± 0.78 mm, non-dominant, 2.82 ± 0.75 mm) and the lowest sensitivity of the little finger (dominant: 3.18 ± 0.88 mm, non-dominant:
3.01 ± 0.71 mm). Using the dynamic discrimination test, we found out that the most sensitivity was of
the index finger (dominant, 2.44 ± 0.71 mm, non-dominant, 2.42 ± 0.52 mm) and the lowest of the little finger (dominant, 2.67 ± 0.88 mm, non-dominant, 2.66 ± 0.71 mm). Overall, using t-test at the significance level of p = 0.05, there was no significant difference in the sensitivity of the fingers in pairs between the dominant and non-dominant hand.
Conclusion
. The difference in sensitivity was not statistically significant between pairs of fingers and toes of the surveyed sensibility between the dominant and non-dominant hand (p> 0.05). Therefore, in order to monitor the recovery of sensibility, the sensibility of injured fingertips can be compared with the sensibility in fingers of opposite healthy hand.

30.06.2022. Original Scientific Articles
Magnetic resonance imaging of the heart as a method of long-term monitoring of right heart function after tetralogy of Fallot surgery

By Biljana Milinković, Jelena Milić, Dejan Bokonjić, Verica Prodanović, Bojan Joksimović, Siniša Ristić

28.12.2019. Original Scientific Articles
Impact of elapsed time between first symptoms and diagnosis of celiac disease on psycho-physical functioning and social life of children and adolescents

By Biljana Stojanović-Jovanović, Stevan Jovanović, Biljana Vuletić

28.06.2012. Original Scientific Articles
Učešće medicinskih sestara u rješavanju akutnih komplikacija dijabetesa

By Mirjana Stamenović, Ljiljana Milović, Natalija Hadživuković, Jelena Pavlović, Sandra Joković

28.12.2020. Reviews
Importance of documentation in nursing practice

By Amajla Topuz, Ivana Miljković

Nursing is an established discipline that helps people in having a productive and healthy life as well as in coping with health problems in the best possible way using established skills. The application of nursing interventions and measures based on the analysis and assessment of patient needs, problems and difficulties observed, and his or her abilities as well as on a continuous assessment and verification of the results obtained is carried out by means of the healthcare process. The rational and logical basis for defining and solving patient's problems is within the scope of healthcare process. Professional networking as well as the networking of all hierarchical structures is a priority where the filing of nursing documentation in a centralized information system is concerned. Nursing documentation is used to establish effective communication between non-medical and medical staff, between nurses and, between families, as well as to establish effective communication with the healthcare system during the overall patient care process.

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