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Vitamin D and atherosclerosis

Olivera Rašević ,
Olivera Rašević

Faculty of Medicine, Foca, University of East Sarajevo, Lukavica, Bosnia and Herzegovina

Maida Mulić ,
Maida Mulić

University Clinical Center Tuzla, Tuzla, Bosnia and Herzegovina

Maja Vuković ,
Maja Vuković

Faculty of Medicine, Foca, The Republic of Srpska, Bosnia and Herzegovina, University of East Sarajevo, Lukavica, Bosnia and Herzegovina

Vesna Lazić ,
Vesna Lazić
Contact Vesna Lazić

Public Health Institute of the Republic of Srpska, Banja Luka, Bosnia and Herzegovina

Biljana Mijović ,
Biljana Mijović

Faculty of Medicine Foča, University of East Sarajevo, Lukavica, Bosnia and Herzegovina

Miloš Maksimović
Miloš Maksimović

Institute of Hygiene with Medical Ecology, Faculty of Medicine , University of Belgrade, Belgrade, Serbia


Cardiovascular diseases rank first on the mortality list globally or 31%. The basic measure of prevention in accordance with the recommendations of the World Health Organization is a change in risk lifestyle in terms of diet, physical activity, tobacco and alcohol consumption. Vitamin D was previously recognized as a regulator of calcium and phosphorus ratio, bone remodeling or the main controller of skeletal pathophysiology. However, vitamin D enjoys great interest in clinical and epidemiological research in terms of its possible impact on reducing the risk of cardiovascular diseases. Among other things, vitamin D deficiency is associated with an increased risk of endothelial dysfunction. Although the deficiency has been identified as a risk marker for cardiovascular diseases, the mechanism of action of vitamin D on the path from endothelial dysfunction to cardiovascular diseases has not been fully revealed. The findings in this segment of activity of vitamin D would be significant in terms of reducing morbidity and mortality from cardiovascular diseases.


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