Home Current Archive Editorial board
News Contact
Original Scientific Articles

Sex-dependent differences in patients treated with regular hemodialysis

Ljubica Mitev Prokopović ,
Ljubica Mitev Prokopović
Contact Ljubica Mitev Prokopović

Clinic for Nephrology, Klinički centar Srbije, Belgrade, Serbia

Miodrag Sokolović ,
Miodrag Sokolović

General Hospital Leskovac, Klinički centar Srbije, Belgrade, Serbia

Branimir Haviža Lilić ,
Branimir Haviža Lilić

Medical Center Pirot, Klinički centar Srbije, Belgrade, Serbia

Miomir Prokopović
Miomir Prokopović

General Hospital Leskovac, Klinički centar Srbije, Belgrade, Serbia


Introduction. The aims of the study were to find out sex differences among patients starting regular hemodialysis (HD) in 2014 and to check whether these differences change over a five-year period.

Methods. The retrospective five-year study included 35 patients (24 men; 11 women) starting HD in HD centers in Leskovac and Pirot in 2014. Demographic data, clinical data, laboratory findings, and medication used for examined patients were taken from medical records.

Results. A comparison of patients of different sexes at the beginning of the study showed that women were significantly older (70.55 ± 13.27 vs. 58.88 ± 15.27 years), but diabetes and hypertension were more frequent causes of chronic kidney disease in men. Women had significantly lower body mass index and serum creatinine level than men in the first year of the study. During all five years, the HD adequacy index spKt/V was higher in women than in men, but the difference reached statistical significance only in the third year (1.4 ± 0.2 vs. 1.2 ± 0.2). Serum iPTH level was higher in women than in men in almost the entire study period. There was no significant sex difference in blood pressure, type of vascular access, number of HD hours per week, in the percentage of patients who used erythropoiesis-stimulating agents or phosphate binders. During the study period 10 (42.7%) men and five (45.5%) women died and the most frequent causes of death were cerebrovascular and cardiovascular diseases.

Conclusion. The study revealed several differences between men and women on regular HD, but no treatment inequality was found. 


Authors retain copyright. This work is licensed under a Creative Commons Attribution 4.0 International License. Creative Commons License

Article metrics

Google scholar: See link

The statements, opinions and data contained in the journal are solely those of the individual authors and contributors and not of the publisher and the editor(s). We stay neutral with regard to jurisdictional claims in published maps and institutional affiliations.