Thyroid Dysfunction in Patients with Multiple Sclerosis: Prevalence and Associated Risk Factors
Introduction: Thyroid dysfunction has been identified as one of the most common comorbidities in people with multiple sclerosis (pwMS). This study aimed to determine the prevalence of thyroid disease and vitamin D levels in patients with MS compared to the general population, and to assess the potential impact of thyroid status and vitamin D levels...
By Daliborka Tadić, Sanja Grgić, Aleksandra Dominović Kovačević, Zoran Vukojević, Gabrijela Malešević, Valentina Soldat Stankovic
Swelling of the optic nerve head due to the coexistence of idiopathic intracranial hypertension and optic nerve drusen
Introduction. Optic nerve head drusen (ONHD) is one of the most common congenital disorder of the optic nerve with prevalence from 0,5-2% in general population. Idiopathic intracranial hypertension is a condition that occurs in children, unlike adults, regardless of gender or the presence of obesity. Both conditions in children present on the eye a...
By Željko Maraš, Tanja Kalezić, Bojan Joksimović, Radmila Balaban Djurević
Familiarity of speech and language therapists and hearing therapists in Bosnia and Herzegovina with contemporary auditory perception treatment approaches
Introduction. Modern approaches to auditory perception therapy are essential for the effective rehabilitation of individuals with hearing impairments. Speech and language therapists and hearing therapists are central to planning and delivering interventions that are grounded in current scientific knowledge and tailored to the individual needs of ea...
By Tijana Simić
Contemporary management of inguinal hernia: from global epidemiology to personalized care
Inguinal hernia represents a significant global health challenge, with more than 20 million operations performed annually. This paper provides a comprehensive review of contemporary practice, critically analyzing the evolution of treatment from the concept of the “gold standard” toward a personalized approach. The study integrates the l...
By Rade Miletić, Nenad Lalović, Siniša Kojić
Metformin-associated hepatotoxicity: a literature review
Metformin (dimethyl biguanide) is an oral antidiabetic agent and one of the most commonly prescribed medications in endocrinology. In addition to its primary use in treating type 2 diabetes, it has a broader range of indications and is generally considered to have a favorable safety profile. The most common side effects are gastrointestinal, includ...
By Goran Bokan, Zoran Mavija
The prognostic significance of HER2 in gastric adenocarcinoma
Introduction. Gastric adenocarcinoma is a major cause of global cancer mortality. The HER2 receptor plays a critical role in cell proliferation and survival and is overexpressed or amplified in a subset of gastric cancers, particularly of the intestinal type. The objective of this study was to evaluate HER2 protein expression and gene amplification...
By Mirjana Ćuk, Radoslav Gajanin, Svjetlana Kulić, Milena Vasić Milanović
Two-tiered serology in patients with Lyme neuroborreliosis
Introduction. Lyme borreliosis is a multisystem infectious disease caused by Borrelia burgdorferi sensu lato complex. It is transmitted by Ixodes ticks. Apart from erythema migrans, other manifestations require laboratory confirmation. The aim of our study was to analyze the results of Two-Tiered Testing in patients with possible Lyme neuroborrelio...
By Tatjana Roganović, Miloš Korać, Borut Bosančić, Višnja Mrdjen, Ljiljana Božić, Andjela Bojanić
Dry needling in cervical pain therapy: literature review
Neck pain, considering its prevalence and rate of disability, represents a significant public health problem, and we believe that the promotion of new effective methods is necessary in its treatment. Among the many therapeutic possibilities described so far, one such is dry needling (DN). This literature review aims to analyze how effective dry nee...
By Bojan Pavlović, Ana Pavlović
Robotic colorectal surgery: experiences, challenges and opportunities through our own research
Robotic colorectal surgery has revolutionized minimally invasive surgical techniques, offering numerous advantages over traditional approaches. Enhanced precision, reduced blood loss, shorter hospital stays, and improved patient outcomes are among the key benefits. However, high costs and technical complexities limit its widespread adoption.This st...
By Igor Černi, Dragan Vanovac
Examining 25-Year Trends of Type 1 Diabetes Incidence in Pediatric Population Aged 0-14 of the Republic of Srpska
Introduction. Data on newly diagnosed cases of type 1 diabetes and the incidence of this disease are very significant. Studies like this one, with an analysis of incidence over the past 25 years, help not only locally but also globally.Methods. The primary source of data is hospital records from hospital centers in Republic of Srpska. The secondary...
By Gordana Bukara-Radujković